Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700986 | 0.77 | CA2 (0.57) | CA2CNR1CCKAR | |
| SCHEMBL10467765 | 0.75 | ALDH1A1 (0.56) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2614665 | 0.74 | CNR1 (0.54) | CA2CNR1CCKAR | |
| SCHEMBL4238494 | 0.73 | CA2 (0.61) | CA2CNR1CCKARBRD4 | |
| SCHEMBL30437414 | 0.73 | CA2 (0.66) | CA2KDM4ECNR1MAPK1CCKAR | |
| Hydrochloric Acid SCHEMBL2114102 | 0.73 | CNR1 (0.53) | CA2CNR1CCKAR | |
| SCHEMBL5135088 | 0.73 | KDM4E (0.60) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3374110 | 0.71 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7242222 | 0.71 | APAF1 (0.64) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28568569 | 0.70 | CA2 (0.71) | CA2KDM4ECNR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292375-A | Substituted alkoxypyridylindolesulfonamides | 优时比制药有限公司 | 2021-01-29 | — | — | CN | disclosed |