Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534335 | 0.88 | TTR (0.42) | PARK7TTRLMNASCN2AALDH1A1 | |
| SCHEMBL28916685 | 0.83 | CHRM5 (0.46) | — | |
| SCHEMBL28432133 | 0.80 | ALDH1A1 (0.52) | PARK7SCN2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL28587504 | 0.80 | CA1 (0.43) | TTRLMNAALDH1A1CASP3APP | |
| SCHEMBL30704878 | 0.79 | CASP3 (0.59) | PARK7TTRLMNASCN2AALDH1A1 | |
| SCHEMBL2551295 | 0.79 | CASP3 (0.59) | PARK7TTRLMNASCN2AALDH1A1 | |
| SCHEMBL20534614 | 0.78 | CA1 (0.44) | PARK7TTRCASP3CA1CA2 | |
| SCHEMBL28584419 | 0.78 | PIM1 (0.45) | ALDH1A1CASP3KMT2AMEN1CA1 | |
| SCHEMBL28581855 | 0.78 | CA2 (0.44) | LMNAALDH1A1CASP3CA1CA2 | |
| SCHEMBL28588483 | 0.78 | CASP3 (0.63) | TTRALDH1A1CASP3APPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961060-B | Preparation method of spiroheterocyclic 2, 3-dihydrobenzofuran compound with optical activity | 遵义医科大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111961060-A | Preparation method of spiroheterocyclic 2, 3-dihydrobenzofuran compound with optical activity | 遵义医科大学 | 2020-11-20 | — | — | CN | disclosed |