Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577987 | 1.00 | LTA4H (0.40) | LTA4HCHRM4ALDH1A1HTTCPT1A | |
| SCHEMBL23632390 | 0.87 | LMNA (0.45) | LTA4HALDH1A1POLBL3MBTL1 | |
| SCHEMBL23632389 | 0.87 | LMNA (0.45) | LTA4HALDH1A1POLBL3MBTL1 | |
| SCHEMBL28612839 | 0.81 | POLB (0.39) | CHRM4ALDH1A1HTTKMT2APOLB | |
| SCHEMBL28612840 | 0.81 | POLB (0.39) | CHRM4ALDH1A1HTTKMT2APOLB | |
| SCHEMBL28610910 | 0.80 | GPR6 (0.35) | CHRM4KMT2APOLB | |
| SCHEMBL28610908 | 0.80 | GPR6 (0.35) | CHRM4KMT2APOLB | |
| SCHEMBL28593230 | 0.78 | RORC (0.43) | — | |
| SCHEMBL28593228 | 0.78 | RORC (0.43) | — | |
| SCHEMBL30075126 | 0.77 | MEN1 (0.49) | ALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |