Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271787 | 0.97 | — | — | |
| Bromide SCHEMBL8744270 | 0.93 | — | — | |
| Acetic Acid SCHEMBL29114522 | 0.79 | CA1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL5461997 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28201228 | 0.71 | TSHR (0.37) | KDM4EPMP22ATM | |
| Hydrochloric Acid SCHEMBL27539808 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL28343942 | 0.69 | — | — | |
| SCHEMBL28715663 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL11548042 | 0.68 | DNM1 (0.42) | — | |
| SCHEMBL6906542 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |