Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596718 | 0.83 | LMNA (0.49) | LMNARECQLMAPTRAB9ANPC1 | |
| Benzoic Acid SCHEMBL11769152 | 0.82 | LMNA (0.49) | LMNARECQLMAPTRAB9ANPC1 | |
| SCHEMBL27448144 | 0.78 | LMNA (0.44) | LMNARECQLMAPTRAB9ANPC1 | |
| SCHEMBL9093296 | 0.75 | LMNA (0.51) | LMNAMAPTRAB9ANPC1ATM | |
| SCHEMBL27818447 | 0.75 | LMNA (0.51) | LMNARECQLMAPTRAB9ANPC1 | |
| SCHEMBL11287380 | 0.74 | LMNA (0.54) | LMNARECQLMAPTRAB9ANPC1 | |
| SCHEMBL1720153 | 0.74 | AKT1 (0.52) | LMNARECQLMAPTRAB9ANPC1 | |
| Metamfepramone SCHEMBL10505245 | 0.72 | PGR (0.63) | LMNAMAPTRAB9ANPC1ATM | |
| Metamfepramone SCHEMBL309430 | 0.72 | PGR (0.63) | LMNAMAPTRAB9ANPC1ATM | |
| SCHEMBL28682238 | 0.72 | PGR (0.53) | LMNARECQLMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961138-B | Polysubstituted chromone derivative and synthetic method thereof | 齐鲁工业大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-112961138-A | Polysubstituted chromone derivative and synthetic method thereof | 齐鲁工业大学 | 2021-06-15 | — | — | CN | disclosed |