Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 2/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26548746 | 0.79 | FDPS (0.48) | FDPSGRM5PROKR1LNPEP | |
| SCHEMBL12093734 | 0.78 | GRM5 (0.45) | FDPSGRM5ABL1AXLMERTK | |
| SCHEMBL12247661 | 0.75 | GRM5 (0.45) | FDPSGRM5AXLMERTKLRRK2 | |
| SCHEMBL17396860 | 0.75 | LOX (0.40) | FDPSGRM5ABL1LRRK2LNPEP | |
| SCHEMBL31403631 | 0.75 | NOS3 (0.52) | FDPSABL1LNPEPLOXLOXL2 | |
| SCHEMBL13791457 | 0.73 | GRM5 (0.46) | GRM5ABL1AXLMERTKLRRK2 | |
| SCHEMBL3927522 | 0.73 | CCR1 (0.57) | PROKR1 | |
| SCHEMBL30496425 | 0.73 | CCR1 (0.57) | PROKR1 | |
| SCHEMBL190625 | 0.72 | GRM5 (0.51) | GRM5PIK3C3 | |
| SCHEMBL2379178 | 0.71 | LNPEP (0.46) | FDPSABL1LNPEPLOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112166113-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-01-01 | — | — | CN | disclosed |