Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 9/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580893 | 0.79 | FDPS (0.44) | FDPSLNPEPPROKR1GRM5 | |
| SCHEMBL26548744 | 0.79 | NOS1 (0.44) | FDPSHRH4MAPK10MAPK14 | |
| SCHEMBL26548519 | 0.78 | CCR1 (0.52) | FDPSHRH4MAPK10MAPK14 | |
| SCHEMBL26550280 | 0.77 | FDPS (0.48) | FDPSHRH4PROKR1MAPK10MAPK14 | |
| SCHEMBL26548751 | 0.73 | MAPK14 (0.40) | FDPSHRH4MAPK10MAPK14 | |
| SCHEMBL26550285 | 0.72 | MAPK14 (0.41) | FDPSHRH4MAPK10MAPK14 | |
| SCHEMBL26547682 | 0.71 | CYP2C9 (0.43) | HRH4MAPK10MAPK14 | |
| SCHEMBL26550286 | 0.71 | HTR7 (0.40) | FDPSHRH4MAPK10MAPK14 | |
| SCHEMBL15102638 | 0.71 | MAPK14 (0.42) | FDPSHRH4MAPK10MAPK14 | |
| SCHEMBL12247661 | 0.70 | GRM5 (0.45) | FDPSLNPEPGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |