SCHEMBL28583258

SCHEMBL28583258

CS(=O)(=O)NC(=O)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
TGFBR1 P36897 1/20 0.33
TDP1 Q9NUW8 1/20 0.30
CA1 P00915 1/20 0.30
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746442 0.82 CA2 (0.33) CA2TDP1LMNAALOX15BLM
SCHEMBL1751607 0.77
SCHEMBL28544067 0.74 TGFBR1 (0.34) CA2TGFBR1CA1BLM
SCHEMBL28349894 0.72 TGFBR1 (0.33) TGFBR1
SCHEMBL28344170 0.72 TGFBR1 (0.33) TGFBR1TDP1
SCHEMBL208790 0.71
SCHEMBL28527888 0.70 TGFBR1 (0.32) TGFBR1
SCHEMBL19955899 0.70 CA2 (0.36) CA2TDP1LMNAALOX15BLM
SCHEMBL194405 0.70 TGFBR1 (0.39) CA2TGFBR1TDP1
SCHEMBL27253156 0.69 CA2 (0.47) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113045609-A Tetrahedral configuration zero-field cobalt single ion magnet and preparation method and application thereof 南通大学 2021-06-29 CN claimed
CN-113365617-A Carbon monoxide prodrugs for the treatment of medical conditions 乔治亚州立大学研究基金会股份有限公司 2021-09-07 CN disclosed
CN-113045609-A Tetrahedral configuration zero-field cobalt single ion magnet and preparation method and application thereof 南通大学 2021-06-29 CN disclosed
CN-113045609-A Tetrahedral configuration zero-field cobalt single ion magnet and preparation method and application thereof 南通大学 2021-06-29 CN disclosed