SCHEMBL194405

SCHEMBL194405

C=C(C)C(=O)NS(C)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.39
CA2 P00918 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.33
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463470 0.79 TGFBR1 (0.39) TGFBR1ALDH1A1TDP1KDM4ERXFP1
SCHEMBL4422753 0.77 TDP1 (0.39) TGFBR1CA2ALDH1A1TDP1KDM4E
SCHEMBL11546233 0.77 TGFBR1 (0.38) TGFBR1ALDH1A1TDP1KDM4ERXFP1
Ammonia Solution, Strong SCHEMBL29930752 0.77 TGFBR1 (0.38) TGFBR1ALDH1A1TDP1KDM4ERXFP1
SCHEMBL28915783 0.77 TGFBR1 (0.38) TGFBR1ALDH1A1TDP1KDM4ERXFP1
SCHEMBL13659289 0.76 CA2 (0.38) CA2ALDH1A1TDP1
Potassium Ion SCHEMBL11546232 0.75 TGFBR1 (0.36) TGFBR1ALDH1A1TDP1KDM4E
SCHEMBL195115 0.75 TGFBR1 (0.41) TGFBR1ALDH1A1TDP1KDM4E
SCHEMBL13545217 0.75 CA2 (0.33) CA2
SCHEMBL15783837 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171451-A Homo- and copolymers of (meth)acrylic acid and their salts; calcium carbonate saturation ratio retained; antiscaling agents, corrosion resistance NALCO CHEMICAL COMPANY (US) 1992-12-15 US claimed
US-20240391904-A1 DIHYDROPYRIMIDINE BASED COMPOUND, PREPARATION METHOD THEREFOR AND USE OF THEREOF CHENGDU SHIBEIKANG BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2024-11-28 US disclosed
EP-4410785-A1 DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Chengdu Shibeikang Biomedical Technology Co., Ltd. (CN) 2024-08-07 EP disclosed
WO-2023046133-A1 DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 成都施贝康生物医药科技有限公司 2023-03-30 WO disclosed
CN-113801097-B Dihydropyrimidine compound, preparation method and application thereof 成都施贝康生物医药科技有限公司 2022-11-22 CN disclosed
US-20160178816-A1 NEAR-INFRARED-ABSORBING COMPOSITION, NEAR-INFRARED CUT FILTER OBTAINED USING SAME, PROCESS FOR PRODUCING SAID CUT FILTER, CAMERA MODULE AND PROCESS FOR PRODUCING SAME, AND SOLID PHOTOGRAPHING ELEMENT FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed
US-20160178816-A1 NEAR-INFRARED-ABSORBING COMPOSITION, NEAR-INFRARED CUT FILTER OBTAINED USING SAME, PROCESS FOR PRODUCING SAID CUT FILTER, CAMERA MODULE AND PROCESS FOR PRODUCING SAME, AND SOLID PHOTOGRAPHING ELEMENT FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed
US-9365515-B2 Oxime ester photoinitiators BASF SE (DE) 2016-06-14 US disclosed
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2014-11-13 US disclosed
US-8524425-B2 Oxime ester photoinitiators BASF SE (DE) 2013-09-03 US disclosed
US-20090246481-A1 DISPERSION OF WATER-INSOLUBLE COLORANT, METHOD OF PRODUCING SUBSTANCE CONTAINING WATER-INSOLUBLE COLORANT, FINE PARTICLES OF WATER-INSOLUBLE COLORANT, DISPERSING AGENT FOR WATER-INSOLUBLE COLORANT, AND RECORDING LIQUID, INK SET, PRINTED ARTICLE, METHOD OF FORMING IMAGE AND IMAGE FORMING APPARATUS USING THE SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-7556843-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-07-07 US disclosed
US-20080206658-A1 Compositions Containing Anthraquinone Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-08-28 US disclosed
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-04-24 US disclosed
US-20070259278-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-11-08 US disclosed
EP-1794823-A2 MULTI-LAYER POLYELECTROLYTE MEMBRANE Arkema Inc. (US) 2007-06-13 EP disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
WO-2006019508-A2 MULTI-LAYER POLYELECTROLYTE MEMBRANE ARKEMA INC. (US) 2006-02-23 WO disclosed
US-5571642-A LIGHT SENSITIVE ELEMENTS WITH CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-11-05 US disclosed
EP-0029168-A1 Polymers, process for their preparation and their use in preparing photographic emulsions and photographic materials Agfa-Gevaert AG (DE) 1981-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391904-A1 DIHYDROPYRIMIDINE BASED COMPOUND, PREPARATION METHOD THEREFOR AND USE OF THEREOF P2RX3, P2RX6, P2RX7 TGFBR1 2089/4885CA2 1736/4885ALDH1A1 685/4885
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes ZKSCAN2, INCENP, CRY2 TGFBR1 2026/4885CA2 41/4885ALDH1A1 1669/4885
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS CBR3, OR10J3, CHRM1 TGFBR1 2429/4885CA2 1701/4885ALDH1A1 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.