SCHEMBL2858366

SCHEMBL2858366

CCOC(OCC)OC(c1ccccc1)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TTR P02766 1/20 0.33
ALOX15 P16050 1/20 0.32
THRB P10828 1/20 0.32
POLB P06746 2/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
KCNN4 O15554 1/20 0.32
MAPT P10636 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858368 0.81 L3MBTL1 (0.37) L3MBTL1ALDH1A1CYP2C19CYP2D6HSD17B10
SCHEMBL7184767 0.77 CYP2D6 (0.38) ALDH1A1CYP2C19CYP2D6HSD17B10MEN1
SCHEMBL2856854 0.70 CES1 (0.42) ALDH1A1CYP2C19SMN1; SMN2MEN1KMT2A
SCHEMBL12918998 0.70 L3MBTL1 (0.34) L3MBTL1ALDH1A1CYP2C19CYP2D6HSD17B10
SCHEMBL2857689 0.69 ALDH1A1 (0.39) ALDH1A1CYP2C19CYP2D6HSD17B10MEN1
SCHEMBL22188641 0.69 ALDH1A1 (0.34) L3MBTL1ALDH1A1CYP2C19CYP2D6HSD17B10
SCHEMBL27451412 0.68 ALDH1A1 (0.41) L3MBTL1ALDH1A1CYP2C19CYP2D6HSD17B10
SCHEMBL27985209 0.68 ALDH1A1 (0.41) L3MBTL1ALDH1A1CYP2C19CYP2D6HSD17B10
SCHEMBL15359072 0.66 ALDH1A1 (0.37) ALDH1A1CYP2C19CYP2D6SMN1; SMN2MEN1
SCHEMBL25769051 0.66 ALDH1A1 (0.37) ALDH1A1CYP2C19CYP2D6SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
EP-1655323-A2 Toner composition Xerox Corporation (US) 2006-05-10 EP disclosed
US-4857434-A Radiation curable liquid (meth) acrylated polymeric hydrocarbon maleate prepolymers and formulations containing same W. R. GRACE & CO. (US) 1989-08-15 US disclosed
EP-0261890-A2 Radiation curable polymers W.R. Grace & Co.-Conn. (US) 1988-03-30 EP disclosed