SCHEMBL2858368

SCHEMBL2858368

CCOC(OCC)OC(OCC)OCC.OC(c1ccccc1)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
CYP2C19 P33261 3/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP2D6 P10635 2/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 1/20 0.36
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
ALOX15 P16050 1/20 0.35
TTR P02766 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
KCNN4 O15554 1/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858366 0.81 L3MBTL1 (0.34) L3MBTL1CYP2C19ALDH1A1CYP2D6HSD17B10
Benzene SCHEMBL28283896 0.77 THRB (0.59) L3MBTL1THRB
SCHEMBL7184769 0.74 ALDH1A1 (0.41) CYP2C19ALDH1A1CYP2D6HSD17B10MEN1
SCHEMBL12918998 0.74 L3MBTL1 (0.34) L3MBTL1CYP2C19ALDH1A1CYP2D6HSD17B10
Methoxymethane SCHEMBL2856857 0.73 KCNN4 (0.48) CYP2C19ALDH1A1KMT2AALOX15SMN1; SMN2
SCHEMBL7173455 0.72 CYP1A2 (0.48) CYP2C19ALDH1A1CYP2D6HSD17B10MEN1
SCHEMBL36629 0.72 CYP1A2 (0.48) CYP2C19ALDH1A1CYP2D6HSD17B10MEN1
SCHEMBL27451412 0.72 ALDH1A1 (0.41) L3MBTL1CYP2C19ALDH1A1CYP2D6HSD17B10
SCHEMBL27985209 0.72 ALDH1A1 (0.41) L3MBTL1CYP2C19ALDH1A1CYP2D6HSD17B10
SCHEMBL868849 0.69 THRB (0.71) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
EP-1655323-A2 Toner composition Xerox Corporation (US) 2006-05-10 EP disclosed
US-4857434-A Radiation curable liquid (meth) acrylated polymeric hydrocarbon maleate prepolymers and formulations containing same W. R. GRACE & CO. (US) 1989-08-15 US disclosed
EP-0261890-A2 Radiation curable polymers W.R. Grace & Co.-Conn. (US) 1988-03-30 EP disclosed
US-4605465-A SKIN-FORMING; NONSAGGING; COATINGS, PHOTORESISTS; GASKETS; SEALS; ADHESIVES W. R. GRACE & CO. (US) 1986-08-12 US disclosed
US-4537805-A Reactive plastisol dispersion W. R. GRACE & CO. (US) 1985-08-27 US disclosed