Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154095 | 0.85 | MAPK1 (0.42) | CYP2D6ALDH1A1CYP2C19HSD17B10ALOX15 | |
| SCHEMBL7184769 | 0.77 | ALDH1A1 (0.41) | CYP2D6ALDH1A1CYP2C19HSD17B10ALOX15 | |
| SCHEMBL2856854 | 0.77 | CES1 (0.42) | ALDH1A1CYP2C19ALOX15MAPK1CYP3A4 | |
| SCHEMBL2858366 | 0.77 | L3MBTL1 (0.34) | CYP2D6ALDH1A1CYP2C19HSD17B10ALOX15 | |
| SCHEMBL2857689 | 0.76 | ALDH1A1 (0.39) | CYP2D6ALDH1A1CYP2C19HSD17B10ALOX15 | |
| SCHEMBL982542 | 0.72 | ALDH1A1 (0.37) | CYP2D6ALDH1A1CYP2C19ALOX15MAPK1 | |
| SCHEMBL25769051 | 0.72 | ALDH1A1 (0.37) | CYP2D6ALDH1A1CYP2C19ALOX15MAPK1 | |
| SCHEMBL15359072 | 0.72 | ALDH1A1 (0.37) | CYP2D6ALDH1A1CYP2C19ALOX15MAPK1 | |
| SCHEMBL21823972 | 0.72 | MAPK1 (0.40) | CYP2D6ALDH1A1CYP2C19ALOX15CHRM3 | |
| SCHEMBL4367368 | 0.72 | MAPK1 (0.42) | CYP2D6ALDH1A1CYP2C19HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545064-B1 | Improved printability and other surface characteristics. | AVERY DENNISON CORPORATION | 2003-04-08 | — | — | US | disclosed |
| WO-2001038452-A1 | COATING COMPOSITION | AVERY DENNISON CORPORATION (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-0246918-B1 | Curable prepolymers | GRACE W R & CO (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0219857-B1 | STORAGE STABLE (METH)ACRYLATE PLASTISOLS | W.R. Grace & Co.-Conn. (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0406921-A2 | Storage stable (meth) acrylate plastisols | W.R. GRACE & CO. (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4857434-A | Radiation curable liquid (meth) acrylated polymeric hydrocarbon maleate prepolymers and formulations containing same | W. R. GRACE & CO. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0287020-A2 | Aqueous developable, curable composition of matter | W.R. Grace & Co.-Conn. (US) | 1988-10-19 | — | — | EP | disclosed |
| EP-0261890-A2 | Radiation curable polymers | W.R. Grace & Co.-Conn. (US) | 1988-03-30 | — | — | EP | disclosed |
| EP-0246918-A1 | Curable prepolymers | W.R. Grace & Co.-Conn. (US) | 1987-11-25 | — | — | EP | disclosed |
| EP-0240939-A2 | Storage stable, heat curable, coating composition | W.R. Grace & Co.-Conn. (US) | 1987-10-14 | — | — | EP | disclosed |
| EP-0238863-A2 | Uv or heat curable reinforced elastomer compositions | W.R. Grace & Co.-Conn. (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4677179-A | Storage stable, heat curable, coating composition | W. R. GRACE (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0219857-A2 | Storage stable (meth)acrylate plastisols | W.R. Grace & Co.-Conn. (US) | 1987-04-29 | — | — | EP | disclosed |
| US-4132812-A | FREE RADICAL INITIATOR | W. R. GRACE & CO. (US) | 1979-01-02 | — | — | US | disclosed |
| US-4117196-A | PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS | W. R. GRACE & CO. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4117017-A | PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR | W. R. GRACE & CO. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4080484-A | POLYAMIDE-ACID OR POLYIMIDE | W. R. GRACE & CO. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4020233-A | Heat activated ethylenically unsaturated-polythiol compositions | W. R. GRACE & CO. (US) | 1977-04-26 | — | — | US | disclosed |