Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 7/20 | 0.43 |
| ▸ | ACLY | P53396 | 3/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.40 |
| ▸ | HNF4A | P41235 | 3/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605070 | 0.81 | AKR1C2 (0.50) | AKR1C2AKR1C1DHODHACLYHSD17B1 | |
| SCHEMBL28583832 | 0.73 | GPR35 (0.47) | DHODHALDH1A1 | |
| SCHEMBL28289969 | 0.73 | FABP4 (0.44) | DHODHACMSDHNF4ADHFRMCL1 | |
| SCHEMBL27737464 | 0.73 | LMNA (0.43) | DHODHALDH1A1 | |
| SCHEMBL27737459 | 0.71 | LMNA (0.42) | DHODHALDH1A1 | |
| SCHEMBL27716599 | 0.71 | LMNA (0.42) | DHODHALDH1A1 | |
| SCHEMBL28588381 | 0.71 | PTPN1 (0.49) | AKR1C2AKR1C1DHODHACMSDHNF4A | |
| SCHEMBL28289980 | 0.70 | MAP2 (0.50) | AKR1C2AKR1C1DHODHHNF4AFABP3 | |
| SCHEMBL28583437 | 0.70 | KDM4A (0.41) | DHODHACMSDHNF4ADHFRMCL1 | |
| SCHEMBL28133754 | 0.70 | PDE4A (0.44) | HSD17B1HSD17B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665958-B | Method for preparing polysubstituted 1-naphthoic acid compound under catalysis of ruthenium | 广州大学 | 2021-05-11 | — | — | CN | disclosed |