Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862945 | 0.89 | MEN1 (0.58) | TSHRCYP19A1MEN1KMT2AMAPK1 | |
| SCHEMBL2862802 | 0.89 | MEN1 (0.50) | TSHRACHECYP19A1MEN1KMT2A | |
| SCHEMBL7768882 | 0.89 | MEN1 (0.50) | TSHRACHECYP19A1MEN1KMT2A | |
| SCHEMBL2858670 | 0.83 | CYP2C9 (0.50) | TSHRACHETDP1MEN1KMT2A | |
| SCHEMBL25489564 | 0.81 | TSHR (0.55) | TSHRACHETDP1CYP19A1MLYCD | |
| SCHEMBL2494396 | 0.81 | CYP19A1 (0.67) | TSHRACHETDP1CYP19A1MLYCD | |
| SCHEMBL6239612 | 0.81 | TSHR (0.55) | TSHRACHETDP1CYP19A1MLYCD | |
| SCHEMBL10906233 | 0.79 | TSHR (0.60) | TSHRACHETDP1CYP19A1MLYCD | |
| SCHEMBL11511029 | 0.79 | TSHR (0.60) | TSHRACHETDP1CYP19A1MLYCD | |
| SCHEMBL858049 | 0.79 | TSHR (0.60) | TSHRACHETDP1CYP19A1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107245029-B | Ketone compound and synthesis method thereof | 广东工业大学 | 2021-01-05 | — | — | CN | claimed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| CN-107245029-B | Ketone compound and synthesis method thereof | 广东工业大学 | 2021-01-05 | — | — | CN | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| CN-104877127-A | Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative | XIAMEN SINOPEG BIOTECH CO LTD | 2015-09-02 | — | — | CN | disclosed |
| EP-0800116-B1 | Photoresist composition | MITSUBISHI CHEM CORP (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5759736-A | Photoresist composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0800116-A1 | Photoresist composition | Mitsubishi Chemical Corporation (JP) | 1997-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | TSHR 1973/4885ACHE 4645/4885TDP1 4223/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | TSHR 1973/4885ACHE 4645/4885TDP1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.