SCHEMBL28587285

SCHEMBL28587285

NC(=O)c1ccc(C(N)=S)c(-c2ccccc2Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.43
PARP1 P09874 6/20 0.41
PDK2 Q15119 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
PARP10 Q53GL7 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CSNK2A1 P68400 1/20 0.35
HIPK2 Q9H2X6 1/20 0.35
BCAT2 O15382 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25223943 0.89 GRM2 (0.46) GRM2PARP1PDK2L3MBTL1PARP10
SCHEMBL28176247 0.78 L3MBTL1 (0.42) GRM2L3MBTL1MEN1KMT2APOLB
SCHEMBL29221020 0.77 PARP1 (0.46) PARP1PDK2L3MBTL1PARP10MEN1
SCHEMBL27621512 0.71 BTK (0.50) PARP1PDK2L3MBTL1MEN1KMT2A
SCHEMBL1898665 0.71 BCAT2 (0.59) GRM2MEN1KMT2APOLBMAPT
SCHEMBL29941064 0.71 BCAT2 (0.59) GRM2MEN1KMT2APOLBMAPT
SCHEMBL7114095 0.70 L3MBTL1 (0.59) PARP1PDK2L3MBTL1PARP10MEN1
SCHEMBL27597015 0.70 KEAP1 (0.47) PARP1PDK2L3MBTL1PARP10MEN1
SCHEMBL5713285 0.70 KEAP1 (0.50) GRM2PARP1PDK2L3MBTL1MEN1
SCHEMBL28354753 0.69 PARP1 (0.50) PARP1L3MBTL1PARP10KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979581-B Method for preparing benzothiazole compound from N- (2-bromophenyl) thioamide promoted by visible light 苏州大学 2022-02-25 CN disclosed
CN-112979581-A Method for preparing benzothiazole compound from N- (2-bromophenyl) thioamide promoted by visible light 苏州大学 2021-06-18 CN disclosed