Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 11/20 | 0.62 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13098618 | 0.83 | LTB4R (0.56) | LTB4RSMN1; SMN2CES1NPC1 | |
| SCHEMBL8676795 | 0.82 | PTGER1 (0.63) | LTB4RPTPRCPTGER1PTGER4PTGER3 | |
| SCHEMBL15877228 | 0.81 | PTPRC (0.54) | LTB4RPTPRCBCL2L1 | |
| SCHEMBL5323308 | 0.81 | LTB4R (0.41) | LTB4RPTPRCMAPK1 | |
| SCHEMBL27675976 | 0.79 | GPR35 (0.49) | LTB4RBIDBCL2L1MCL1BAK1 | |
| SCHEMBL28345653 | 0.79 | TSHR (0.41) | LTB4RPTPRC | |
| SCHEMBL4371004 | 0.78 | LTB4R (0.44) | LTB4RPTPRC | |
| SCHEMBL30544 | 0.78 | GPR35 (0.55) | LTB4RBIDBCL2L1MCL1BAK1 | |
| SCHEMBL16807890 | 0.77 | MAPK8 (0.52) | LTB4RPTPRCSMN1; SMN2DAORXFP1 | |
| SCHEMBL17353545 | 0.77 | GPR35 (0.57) | LTB4RBIDBCL2L1MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108840864-B | Preparation method and application of tacrine-heterocyclic conjugate | 中国医学科学院生物医学工程研究所 | 2021-07-27 | — | — | CN | disclosed |