Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858744 | 0.82 | VDR (0.38) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2856205 | 0.76 | ALDH1A1 (0.45) | MAPTALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL6472980 | 0.75 | RAB9A (0.42) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2877573 | 0.73 | RAB9A (0.42) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2858262 | 0.72 | VDR (0.43) | ALDH1A1L3MBTL1RARBPPARA | |
| SCHEMBL2854898 | 0.69 | NPC1 (0.42) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2863419 | 0.68 | RAB9A (0.42) | MAPTALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL28065934 | 0.68 | MAPT (0.53) | MAPTALDH1A1L3MBTL1CYP2D6MEN1 | |
| SCHEMBL14947561 | 0.67 | MAPT (0.49) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL14947562 | 0.67 | MAPT (0.49) | MAPTALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |