Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863419 | 0.86 | RAB9A (0.42) | VDRPPARGPPARAALDH1A1HPGD | |
| SCHEMBL2858257 | 0.83 | VDR (0.63) | VDRPPARGPPARARARBL3MBTL1 | |
| SCHEMBL2855027 | 0.78 | HTT (0.41) | VDRPPARGPPARAALDH1A1HPGD | |
| SCHEMBL2863408 | 0.78 | VDR (0.49) | VDRPPARGPPARAALDH1A1HPGD | |
| SCHEMBL2854602 | 0.75 | ALDH1A1 (0.39) | VDRPPARGPPARAALDH1A1HPGD | |
| SCHEMBL3283557 | 0.74 | LTB4R (0.41) | PPARGPPARAALDH1A1HPGDHTT | |
| SCHEMBL2858749 | 0.72 | MAPT (0.36) | PPARARARBL3MBTL1ALDH1A1 | |
| SCHEMBL2856305 | 0.71 | PPARG (0.37) | PPARGPPARAHPGD | |
| SCHEMBL2863416 | 0.71 | VDR (0.58) | VDRPPARGPPARAALDH1A1HPGD | |
| SCHEMBL2853384 | 0.70 | RAB9A (0.46) | VDRPPARGPPARAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |