Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587829 | 0.89 | SGMS2 (0.44) | SGMS2MRGPRX4FFAR1FFAR4PPIA | |
| SCHEMBL28587775 | 0.84 | FFAR1 (0.53) | FFAR1FFAR4ALKBH1XDH | |
| SCHEMBL28583440 | 0.79 | XDH (0.59) | SGMS2MRGPRX4FFAR1FFAR4PPIA | |
| SCHEMBL28587005 | 0.76 | XDH (0.56) | SGMS2MRGPRX4FFAR1FFAR4PPIA | |
| SCHEMBL28568681 | 0.75 | PDE5A (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28593875 | 0.74 | PDE5A (0.37) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28587828 | 0.73 | FFAR1 (0.52) | MRGPRX4FFAR1FFAR4ALKBH1 | |
| SCHEMBL28593877 | 0.73 | PDE5A (0.39) | PTGER1PDE5APDE4APDE4BPDE4C | |
| SCHEMBL28916533 | 0.72 | XDH (0.53) | SGMS2MRGPRX4FFAR1FFAR4PPIA | |
| SCHEMBL13851581 | 0.69 | POLB (0.63) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | disclosed |