Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 4/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587775 | 0.89 | FFAR1 (0.53) | FFAR1FFAR4ALOX5ALOX5APALKBH1 | |
| SCHEMBL28587829 | 0.84 | SGMS2 (0.44) | FFAR1FFAR4ALKBH1DHODHMRGPRX4 | |
| SCHEMBL28583439 | 0.77 | XDH (0.61) | FFAR1FFAR4ALOX5ALOX5APALKBH1 | |
| SCHEMBL28582832 | 0.75 | MCL1 (0.37) | DHODHMCL1 | |
| SCHEMBL28587004 | 0.74 | ALKBH1 (0.64) | FFAR1FFAR4ALOX5ALOX5APALKBH1 | |
| SCHEMBL28587780 | 0.73 | SGMS2 (0.44) | FFAR1FFAR4ALKBH1MRGPRX4 | |
| SCHEMBL1247999 | 0.72 | MAOB (0.63) | FFAR1FFAR4ALOX5ALOX5APADAMTS4 | |
| SCHEMBL851377 | 0.72 | MEN1 (0.68) | FFAR1FFAR4ALKBH1MAOBMRGPRX4 | |
| SCHEMBL25203039 | 0.71 | NR4A2 (0.71) | FFAR1FFAR4ALKBH1MRGPRX4 | |
| SCHEMBL30903730 | 0.71 | ALOX5 (0.50) | FFAR1FFAR4ALOX5ALOX5APDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | disclosed |