Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.43 |
| ▸ | PPARA | Q07869 | 15/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852529 | 0.95 | PPARA (0.37) | PPARGPPARAPPARDFFAR1LTB4R | |
| SCHEMBL2851882 | 0.92 | PPARA (0.41) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL2855102 | 0.89 | PPARA (0.37) | PPARGPPARAPPARDNPC1ALDH1A1 | |
| SCHEMBL2858864 | 0.74 | VDR (0.49) | PPARGPPARANPC1ALDH1A1RAB9A | |
| SCHEMBL1022002 | 0.74 | MTNR1A (0.44) | PPARGPPARAALDH1A1 | |
| SCHEMBL13604875 | 0.73 | VDR (0.45) | PPARGPPARANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2863408 | 0.72 | VDR (0.49) | PPARGPPARANPC1ALDH1A1RAB9A | |
| SCHEMBL2856534 | 0.69 | VDR (0.42) | PPARGPPARANPC1ALDH1A1RAB9A | |
| SCHEMBL1022007 | 0.68 | ALDH1A1 (0.42) | PPARGPPARAALDH1A1 | |
| SCHEMBL2863404 | 0.68 | VDR (0.68) | PPARGPPARANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |