Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852529 | 0.92 | PPARA (0.37) | PPARAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2858865 | 0.89 | PPARG (0.43) | PPARAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2851882 | 0.81 | PPARA (0.41) | PPARAPPARGPPARD | |
| SCHEMBL2855100 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL2854311 | 0.73 | RXRA (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL2863756 | 0.71 | SRD5A2 (0.38) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL2861743 | 0.70 | HSP90AB1 (0.39) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL2854307 | 0.69 | VDR (0.52) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL2886488 | 0.69 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2ACYP3A4MEN1 | |
| SCHEMBL6155010 | 0.67 | KMT2A (0.41) | ALDH1A1HPGDKMT2ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2010-01-20 | — | — | EP | disclosed |
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |