SCHEMBL285903

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL285904	1.00	HDAC3 (0.41)	HDAC3HDAC4HDAC1HDAC2HDAC8
	SCHEMBL285912	0.93	HDAC6 (0.44)	HDAC3HDAC4HDAC1HDAC2HDAC8
	SCHEMBL286330	0.90	GABRA5 (0.49)	HDAC3HDAC4HDAC1HDAC2HDAC8
	SCHEMBL286404	0.89	CFTR (0.42)	HDAC3HDAC4HDAC1HDAC2HDAC8
	SCHEMBL286288	0.86	GABRA5 (0.45)	GABRA5PHGDH
	SCHEMBL285913	0.86	GABRA5 (0.45)	GABRA5PHGDH
	SCHEMBL285911	0.86	GABRA5 (0.45)	GABRA5PHGDH
	SCHEMBL286636	0.86	LMNA (0.46)	GABRA5BACE1PTGS2NPC1LMNA
	SCHEMBL286635	0.86	LMNA (0.46)	GABRA5BACE1PTGS2NPC1LMNA
	SCHEMBL286468	0.86	POLB (0.40)	GABRA5BACE1PTGS2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.