Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.45 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853388 | 0.96 | CCR1 (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2861243 | 0.92 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2853334 | 0.91 | CCR1 (0.47) | ALDH1A1MAPTCCR1NPSR1HPGD | |
| SCHEMBL2850425 | 0.91 | P2RX7 (0.49) | MAPTPOLBTP53CCR1NPSR1 | |
| SCHEMBL2854847 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2852454 | 0.91 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2859861 | 0.90 | TAAR1 (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2857598 | 0.90 | KMT2A (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2859307 | 0.89 | TSHR (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL2854322 | 0.89 | ABCB1 (0.45) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |