Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917376 | 0.80 | NPC1 (0.60) | NR1H4KDM4ERAB9ATRPV1MAPT | |
| SCHEMBL13153544 | 0.71 | TRPV1 (0.63) | NR1H4KDM4ERAB9ATRPV1MAPT | |
| SCHEMBL28620992 | 0.70 | STAT3 (0.60) | NR1H4LMNAMEN1KMT2A | |
| SCHEMBL28583664 | 0.70 | STAT3 (0.63) | KDM4ECYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL4113612 | 0.68 | KDM4E (0.72) | KDM4ERAB9AMAPTLMNATP53 | |
| SCHEMBL8388736 | 0.68 | TRPV1 (0.55) | KDM4ERAB9ATRPV1NPC1 | |
| SCHEMBL13152704 | 0.66 | HPGD (0.55) | NR1H4KDM4ERAB9ACYP1A2CYP2C19 | |
| SCHEMBL22721254 | 0.66 | RARB (0.60) | NR1H4RAB9AMAPTMEN1NPC1 | |
| SCHEMBL27296313 | 0.66 | MAPT (0.46) | KDM4ERAB9AMAPTMEN1NPC1 | |
| SCHEMBL27286217 | 0.66 | ALDH1A1 (0.64) | NR1H4KDM4ERAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997176-B | 4-chloro-N-substituted phenyl-3-sulfonyl aminobenzamide compound, and preparation and anti-tumor application thereof | 温州医科大学 | 2021-07-02 | — | — | CN | disclosed |