Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594835 | 0.80 | NR1H4 (0.44) | NPC1RAB9ATRPV1NR1H4TP53 | |
| SCHEMBL7294922 | 0.78 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL28617689 | 0.78 | KCNK9 (0.62) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL7303163 | 0.78 | HDAC3 (0.86) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL28583664 | 0.77 | STAT3 (0.63) | SMN1; SMN2ATMTP53KDM4EMAPT | |
| SCHEMBL16678174 | 0.76 | HDAC3 (0.73) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL16677863 | 0.76 | HDAC6 (0.73) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL7303572 | 0.76 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL557111 | 0.75 | HDAC6 (0.71) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL1291198 | 0.75 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997176-B | 4-chloro-N-substituted phenyl-3-sulfonyl aminobenzamide compound, and preparation and anti-tumor application thereof | 温州医科大学 | 2021-07-02 | — | — | CN | claimed |