Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585413 | 0.87 | LMNA (0.56) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL28589842 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL28590432 | 0.87 | LMNA (0.42) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL28594377 | 0.86 | EPHX2 (0.40) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL28596198 | 0.86 | KMT2A (0.47) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL28585572 | 0.85 | ELANE (0.50) | ALDH1A1LMNAHPGDMAPTSMN1; SMN2 | |
| SCHEMBL28586027 | 0.85 | GRM5 (0.43) | ALDH1A1LMNAHPGDMAPTHTT | |
| SCHEMBL28591393 | 0.85 | HPGD (0.43) | ALDH1A1LMNAHPGDMAPTHTT | |
| SCHEMBL28591387 | 0.85 | VNN1 (0.45) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28596139 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |