Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596145 | 0.86 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1HPGDLMNA | |
| SCHEMBL28605211 | 0.86 | LTA4H (0.43) | KMT2AALDH1A1MEN1HPGDLMNA | |
| SCHEMBL28600299 | 0.85 | ELANE (0.51) | KMT2AALDH1A1MEN1NPC1STS | |
| SCHEMBL28585647 | 0.85 | CES2 (0.38) | KMT2AMEN1LMNACES2CES1 | |
| SCHEMBL28591385 | 0.84 | TDP1 (0.41) | KMT2AMEN1HPGDLMNAMAPT | |
| SCHEMBL28590427 | 0.84 | L3MBTL1 (0.41) | KMT2AALDH1A1MEN1HPGDLMNA | |
| SCHEMBL28581294 | 0.83 | CES2 (0.42) | KMT2AALDH1A1MEN1HPGDLMNA | |
| SCHEMBL28589842 | 0.83 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1HPGDLMNA | |
| SCHEMBL28585413 | 0.83 | LMNA (0.56) | KMT2AALDH1A1MEN1HPGDLMNA | |
| SCHEMBL29730112 | 0.77 | MAP4K4 (0.39) | LMNASMN1; SMN2KDM4ECES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |