Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.38 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855711 | 0.92 | P2RX7 (0.42) | KDM4EMAPTCES2NPSR1MAPK14 | |
| SCHEMBL2857600 | 0.91 | CNR1 (0.46) | MAPTNPSR1TP53GAACCR1 | |
| SCHEMBL2854509 | 0.88 | KDM4E (0.50) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2850868 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL2852955 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2859726 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2860826 | 0.87 | KDM4E (0.43) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2856562 | 0.86 | MAPT (0.48) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2860110 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2857230 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |