Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596601 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL29629334 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL754483 | 0.81 | AR (0.46) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL2848169 | 0.81 | TP53 (0.42) | ALDH1A1MAPTMEN1KMT2AHTR2A | |
| SCHEMBL17985004 | 0.78 | CYP19A1 (0.49) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL1711344 | 0.77 | CYP2C9 (0.38) | ALDH1A1MAPTSIRT1PPARG | |
| SCHEMBL72984 | 0.77 | SIRT1 (0.48) | ALDH1A1KMT2AHPGDSIRT1KDM4E | |
| SCHEMBL27893072 | 0.77 | SIRT1 (0.48) | ALDH1A1KMT2AHPGDSIRT1KDM4E | |
| SCHEMBL8927781 | 0.76 | ACHE (0.48) | SIRT1PPARG | |
| SCHEMBL29629339 | 0.76 | ACHE (0.48) | SIRT1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-B | Method for preparing 3-substituted chromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-03-05 | — | — | CN | disclosed |
| CN-115974825-A | Method for preparing 3-substituted chromanone through metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-112898259-B | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-112898259-A | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2021-06-04 | — | — | CN | disclosed |