Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Charcoal, Activated SCHEMBL2025121 | 0.98 | SIRT1 (0.47) | SIRT1CYP19A1CTRCHSD17B10MAOB | |
| SCHEMBL21248251 | 0.91 | MAOB (0.47) | SIRT1CYP19A1CTRCMAOBESR1 | |
| Pyrrole SCHEMBL28505040 | 0.91 | SIRT1 (0.42) | SIRT1CYP19A1CTRCHSD17B10MAOB | |
| Naphthoquinone SCHEMBL1377175 | 0.89 | CYP19A1 (0.43) | SIRT1CYP19A1CTRCHSD17B10MAOB | |
| SCHEMBL17985004 | 0.87 | CYP19A1 (0.49) | SIRT1CYP19A1MAOBALDH1A1ALDH2 | |
| SCHEMBL4806205 | 0.87 | MAPT (0.46) | SIRT1HSD17B10KDM4EADORA3ALDH1A1 | |
| SCHEMBL2854127 | 0.87 | CYP19A1 (0.49) | SIRT1CYP19A1MAOBALDH1A1MAOA | |
| SCHEMBL31547349 | 0.87 | MAPT (0.46) | SIRT1HSD17B10KDM4EADORA3ALDH1A1 | |
| Flavanone SCHEMBL14126568 | 0.85 | MAOB (0.69) | CYP19A1HSD17B10MAOBKDM4EADORA3 | |
| SCHEMBL705946 | 0.83 | CYP19A1 (0.52) | CYP19A1MAOBALDH1A1HPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240122894-A1 | METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2024-04-18 | — | — | US | claimed |
| EP-4259614-A1 | METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF | National University of Singapore (SG) | 2023-10-18 | — | — | EP | claimed |
| CN-116829544-A | Synthesis method of flavonoid dimers and oligomers and application thereof | 新加坡国立大学 | 2023-09-29 | — | — | CN | claimed |
| WO-2023150072-A1 | COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER | SINCLAIR DAVID A (US) | 2023-08-10 | — | — | WO | claimed |
| CN-111574487-B | Preparation method of chiral dihydroisoflavone compound and product thereof | 深圳市宝安区新材料研究院 | 2023-02-21 | — | — | CN | claimed |
| WO-2022124994-A1 | METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-06-16 | — | — | WO | claimed |
| CN-113759034-A | Establishing method of ophiopogon japonicus soup substance standard | 广东一方制药有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-113057250-A | Functional easily-digestible micellar casein powder and preparation method thereof | 甘肃农业大学 | 2021-07-02 | — | — | CN | claimed |
| CN-111574487-A | Preparation method of chiral dihydroisoflavone compound and product thereof | 深圳市前海博扬研究院有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-108241033-B | Method for rapidly detecting content of 6 quality index substances in radix ophiopogonis alcohol extract and application | 大理药业股份有限公司 | 2020-06-30 | — | — | CN | claimed |
| US-20040071745-A1 | Admixture of carotenoids and isoflavonoids for treating cutaneous symptoms of aging | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | claimed |
| US-20040038152-A1 | Method for making printing plate by inkjet deposition on positive-working media | CREO SRL (CA) | 2004-02-26 | — | — | US | claimed |
| WO-2004007200-A1 | METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA | CREO SRL (CA) | 2004-01-22 | — | — | WO | claimed |
| CN-1431209-A | Method for synthesizing molluscacide (Al pinumisoflavone) of pyrane isoflavone and its product | INST OF MILITARY MEDICINE IN D (CN) | 2003-07-23 | — | — | CN | claimed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | claimed |
| US-20020015741-A1 | Method and composition for the accelerated in vivo removal of ethanol | CHEMDAN, LLC | 2002-02-07 | — | — | US | claimed |
| EP-1161540-A1 | GENETIC MANIPULATION OF ISOFLAVONOIDS | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000053771-A1 | GENETIC MANIPULATION OF ISOFLAVONOIDS | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2000-09-14 | — | — | WO | claimed |
| EP-0263553-A2 | Method of inhibiting gene induction | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020015741-A1 | Method and composition for the accelerated in vivo removal of ethanol | ADH1A, ADH1C, ADH5 | SIRT1 1263/4885CYP19A1 1757/4885CTRC 1041/4885 |
| US-20240122894-A1 | METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF | ERG28, MGAM, CTRB2 | SIRT1 1489/4885CYP19A1 875/4885CTRC 57/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | SIRT1 1151/4885CYP19A1 460/4885CTRC 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.