Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | PKM | P14618 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269744 | 0.79 | CYP1A2 (0.50) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL29082949 | 0.73 | ALDH1A1 (0.47) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL29374931 | 0.73 | RAB9A (0.64) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL170196 | 0.73 | RAB9A (0.64) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL11497248 | 0.72 | MMP2 (0.55) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL29746310 | 0.71 | CYP11B1 (0.53) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL29580854 | 0.71 | RAB9A (0.59) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL8783647 | 0.71 | RAB9A (0.59) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL3647009 | 0.71 | CYP11B1 (0.53) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL20951334 | 0.71 | TLR8 (0.50) | ALDH1A1PKMNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074880-A1 | NOVEL QUINOLINE DERIVATIVES AND USES THEREOF | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2025-03-06 | — | — | US | disclosed |
| EP-4337640-A1 | NOVEL QUINOLINE DERIVATIVES AND USES THEREOF | Istituto Europeo di Oncologia S.r.l. (IT) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022238863-A1 | NOVEL QUINOLINE DERIVATIVES AND USES THEREOF | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2022-11-17 | — | — | WO | disclosed |
| EP-4089077-A1 | NOVEL QUINOLINE DERIVATIVES AND USES THEREOF | Istituto Europeo di Oncologia S.r.l. (IT) | 2022-11-16 | — | — | EP | disclosed |
| CN-113185555-B | Pincer-shaped manganese complex and preparation method thereof, related ligand and preparation method thereof, catalyst composition and application | 河北农业大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-113185555-A | Pincer-shaped manganese complex and preparation method thereof, related ligand and preparation method thereof, catalyst composition and application | 河北农业大学 | 2021-07-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074880-A1 | NOVEL QUINOLINE DERIVATIVES AND USES THEREOF | NDC1, CHD1L, NUMA1 | ALDH1A1 4197/4885PKM 1559/4885NPC1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.