Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995308 | 0.86 | AR (0.40) | HSD11B1APLNRARKDM4ESMN1; SMN2 | |
| SCHEMBL28588663 | 0.80 | HSD11B1 (0.48) | HSD11B1CRHR1TACR1SMN1; SMN2 | |
| SCHEMBL6681359 | 0.75 | AR (0.41) | HSD11B1APLNRARKDM4ESMN1; SMN2 | |
| SCHEMBL28995384 | 0.74 | AR (0.40) | HSD11B1APLNRARKDM4ECTSK | |
| SCHEMBL6680112 | 0.74 | APLNR (0.42) | APLNRARKDM4E | |
| SCHEMBL23318473 | 0.73 | AR (0.39) | APLNRARKDM4E | |
| SCHEMBL1263973 | 0.72 | HSD11B1 (0.59) | HSD11B1ARSMN1; SMN2 | |
| SCHEMBL6679512 | 0.72 | ATM (0.39) | APLNRARKDM4ETP53MEN1 | |
| SCHEMBL28291241 | 0.70 | AR (0.44) | HSD11B1APLNRARKDM4E | |
| SCHEMBL6676898 | 0.69 | PIM1 (0.36) | APLNRARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939818-B | Synthetic method of 2- (2, 2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 江苏扬农化工股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-112939818-A | Synthetic method of 2- (2, 2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 江苏扬农化工股份有限公司 | 2021-06-11 | — | — | CN | disclosed |