Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 2/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593853 | 0.88 | HTR6 (0.44) | F10HTR1AHTR7HTR2BHTR6 | |
| SCHEMBL25016025 | 0.85 | F10 (0.45) | F10CNR2HTR4DRD4F2 | |
| SCHEMBL21822222 | 0.85 | F10 (0.44) | F10CNR2HTR4F2KHK | |
| SCHEMBL21822282 | 0.84 | F10 (0.49) | F10CNR2F2KHKACSS2 | |
| SCHEMBL25016029 | 0.82 | ACSS2 (0.42) | F10CNR2HTR4KHKACSS2 | |
| SCHEMBL28582778 | 0.82 | CCR2 (0.48) | F10 | |
| SCHEMBL25015961 | 0.82 | F10 (0.41) | F10CNR2F2 | |
| SCHEMBL28594358 | 0.82 | F10 (0.41) | F10CNR2F2 | |
| SCHEMBL25016722 | 0.81 | F10 (0.44) | F10CNR2KHKACSS2 | |
| SCHEMBL25017934 | 0.80 | F10 (0.48) | F10F2ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |