Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598807 | 0.88 | F10 (0.42) | HTR6HTR4F10ECE1ACSS2 | |
| SCHEMBL28598772 | 0.86 | HTR4 (0.44) | HTR4F10ACSS2PPARGKDM1A | |
| SCHEMBL25017427 | 0.85 | HTR4 (0.43) | HTR6HTR4F10PPARG | |
| SCHEMBL21822848 | 0.85 | F10 (0.51) | HTR4F10ACSS2 | |
| SCHEMBL28582778 | 0.81 | CCR2 (0.48) | F10 | |
| SCHEMBL28582228 | 0.79 | HTR4 (0.45) | HTR4ACSS2CHRM1 | |
| SCHEMBL28916652 | 0.78 | ROCK1 (0.42) | F10ECE1 | |
| SCHEMBL21822742 | 0.76 | F10 (0.45) | F10BRD4 | |
| SCHEMBL21822226 | 0.74 | F10 (0.54) | F10 | |
| SCHEMBL21822222 | 0.73 | F10 (0.44) | HTR4F10ACSS2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |