SCHEMBL28599084

SCHEMBL28599084

Cc1ccc(C(C)COCC(C)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TRPA1 O75762 1/20 0.39
LMNA P02545 1/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A2 P23975 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
HTR1A P08908 1/20 0.37
CASR P41180 1/20 0.36
SRC P12931 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ADRB2 P07550 1/20 0.33
TACR1 P25103 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NR3C1 P04150 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28263806 0.79 TSHR (0.42) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL21349603 0.79 SMN1; SMN2 (0.41) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL20738712 0.78 TRPA1 (0.45) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL8996446 0.74 NR3C1 (0.44) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL15919018 0.74 SRC (0.41) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL9688997 0.74 SRC (0.41) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL29757164 0.73 TRPA1 (0.60) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL599102 0.73 TRPA1 (0.60) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL6546836 0.73 CASR (0.50) KDM4EALDH1A1TRPA1LMNACHRM1
SCHEMBL9090921 0.73 TRPA1 (0.37) KDM4EALDH1A1TRPA1LMNACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113173836-B Method for synthesizing borane-catalyzed symmetrical ether 南京晓庄学院 2023-04-14 CN disclosed
CN-113173836-A Method for synthesizing symmetric ether catalyzed by borane 南京晓庄学院 2021-07-27 CN disclosed