Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19775441 | 0.81 | SRC (0.40) | SRCTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL15919018 | 0.81 | SRC (0.41) | SRCTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL28263806 | 0.78 | TSHR (0.42) | SRCTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL20738712 | 0.76 | TRPA1 (0.45) | SRCTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL19985073 | 0.76 | ESR1 (0.43) | LMNACHRM1SLC6A2ADRA1AHTR2B | |
| SCHEMBL22416799 | 0.76 | ESR1 (0.43) | LMNACHRM1SLC6A2ADRA1AHTR2B | |
| SCHEMBL9090921 | 0.76 | TRPA1 (0.37) | SRCTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL5483548 | 0.76 | CASR (0.38) | SRCTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL6547130 | 0.75 | NR3C1 (0.50) | LMNAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL28599084 | 0.74 | KDM4E (0.40) | SRCTRPA1LMNACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |