Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240061 | 0.86 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL5380872 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL30066901 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL28138447 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL5370015 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL8440245 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL28007657 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL11146721 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL11723850 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL3840366 | 0.80 | P2RX7 (0.49) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121562-B | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113121562-A | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2021-07-16 | — | — | CN | disclosed |