Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.55 |
| ▸ | PTGIR | P43119 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599365 | 0.93 | OPRM1 (0.59) | TP53OPRM1PTGIR | |
| SCHEMBL28602018 | 0.91 | OPRM1 (0.67) | OPRM1PTGIRSIGMAR1CARM1PRMT6 | |
| SCHEMBL28597470 | 0.86 | PTGIR (0.56) | OPRM1PTGIRSIGMAR1CARM1PRMT6 | |
| SCHEMBL28602839 | 0.84 | OPRM1 (0.70) | OPRM1SIGMAR1 | |
| SCHEMBL28613676 | 0.79 | ACHE (0.57) | OPRM1PTGIRCARM1PRMT6 | |
| SCHEMBL20328148 | 0.76 | CARM1 (0.70) | CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL27629597 | 0.73 | CARM1 (0.65) | CARM1PRMT6 | |
| SCHEMBL29186126 | 0.72 | OPRM1 (0.58) | TP53OPRM1SIGMAR1SMN1; SMN2 | |
| SCHEMBL29186101 | 0.72 | TP53 (0.53) | TP53OPRM1SIGMAR1 | |
| SCHEMBL11175459 | 0.72 | CARM1 (0.57) | SIGMAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214139-A | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |