Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | PTGIR | P43119 | 1/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602839 | 0.92 | OPRM1 (0.70) | OPRM1SIGMAR1 | |
| SCHEMBL28599569 | 0.91 | TP53 (0.58) | OPRM1SIGMAR1PTGIRCARM1PRMT6 | |
| SCHEMBL28597470 | 0.88 | PTGIR (0.56) | OPRM1SIGMAR1ACHEPTGIRCARM1 | |
| SCHEMBL28599365 | 0.84 | OPRM1 (0.59) | OPRM1PTGIR | |
| SCHEMBL28613676 | 0.81 | ACHE (0.57) | OPRM1ACHEPTGIRCARM1PRMT6 | |
| SCHEMBL28597364 | 0.80 | OPRM1 (1.00) | OPRM1SIGMAR1ACHE | |
| SCHEMBL28609565 | 0.77 | OPRM1 (0.92) | OPRM1 | |
| SCHEMBL28594948 | 0.76 | OPRM1 (0.66) | OPRM1SIGMAR1ACHECARM1PRMT6 | |
| SCHEMBL28611346 | 0.76 | OPRM1 (1.00) | OPRM1 | |
| SCHEMBL28609709 | 0.76 | OPRM1 (0.71) | OPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214139-A | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |