Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PTGIR | P43119 | 4/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599569 | 0.93 | TP53 (0.58) | OPRM1TP53PTGIR | |
| SCHEMBL28602839 | 0.92 | OPRM1 (0.70) | OPRM1 | |
| SCHEMBL28613676 | 0.88 | ACHE (0.57) | OPRM1PTGIRCHRM5CHRM1CHRM3 | |
| SCHEMBL28602018 | 0.84 | OPRM1 (0.67) | OPRM1PTGIR | |
| SCHEMBL28597470 | 0.80 | PTGIR (0.56) | OPRM1PTGIR | |
| SCHEMBL10964017 | 0.75 | DRD2 (0.54) | OPRM1CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL10963435 | 0.74 | DRD2 (0.53) | OPRM1CHRM1CHRM3 | |
| SCHEMBL28609709 | 0.74 | OPRM1 (0.71) | OPRM1CHRM1CHRM3 | |
| SCHEMBL28602605 | 0.74 | OPRM1 (1.00) | OPRM1 | |
| Oxalic Acid SCHEMBL7327098 | 0.73 | SSTR5 (0.51) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214139-A | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |