SCHEMBL28599880

SCHEMBL28599880

CN(C)c1ccc2c(c1)C=CCN2C

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
SNCA P37840 1/20 0.36
HSD17B10 Q99714 2/20 0.34
TSHR P16473 2/20 0.34
ALOX15 P16050 1/20 0.34
P2RX4 Q99571 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TERT O14746 1/20 0.33
APP P05067 1/20 0.33
PDGFRB P09619 1/20 0.32
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28747930 0.73 MAPT (0.41) ALDH1A1SNCAHSD17B10ALOX15KDM4E
SCHEMBL30548359 0.72 TERT (0.35) ALDH1A1SNCAHSD17B10TSHRALOX15
SCHEMBL30548360 0.72 TERT (0.35) ALDH1A1SNCAHSD17B10TSHRALOX15
SCHEMBL29923722 0.71 BRD4 (0.38) ALDH1A1MAPK1L3MBTL1MAPT
Iodide SCHEMBL30293255 0.70 LMNA (0.39) ALDH1A1SNCATSHRKDM4EKMT2A
SCHEMBL10670398 0.70 CA12 (0.34) KDM4EMEN1KMT2AMAPT
SCHEMBL1198914 0.69 P2RX4 (0.37) ALDH1A1TSHRP2RX4KDM4EMEN1
SCHEMBL29434173 0.69 P2RX4 (0.37) ALDH1A1TSHRP2RX4KDM4EMEN1
Iodide SCHEMBL7101346 0.67 P2RX4 (0.36) ALDH1A1TSHRP2RX4KDM4EMEN1
Hydrochloric Acid SCHEMBL29035745 0.67 MEN1 (0.37) ALDH1A1TSHRP2RX4KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084869-A Abeta based on chemical excitation oxidation1-42Protein nanoparticle, and preparation method and application thereof 华南理工大学 2024-05-28 CN claimed
CN-116589404-A Photosensitizer targeting beta amyloid protein and preparation method and application thereof 华南理工大学 2023-08-15 CN claimed
CN-116589404-B Photosensitizer targeting beta amyloid protein and preparation method and application thereof 华南理工大学 2026-05-15 CN disclosed
CN-118047719-B Be used for Abeta1-42Preparation and application of quinolinium photosensitizer for protein imaging and viscosity imaging 华南理工大学 2024-06-28 CN disclosed
CN-118084869-A Abeta based on chemical excitation oxidation1-42Protein nanoparticle, and preparation method and application thereof 华南理工大学 2024-05-28 CN disclosed
CN-118047719-A Be used for Abeta1-42Preparation and application of quinolinium photosensitizer for protein imaging and viscosity imaging 华南理工大学 2024-05-17 CN disclosed
CN-116589404-A Photosensitizer targeting beta amyloid protein and preparation method and application thereof 华南理工大学 2023-08-15 CN disclosed
CN-113651752-B Synthesis method of 2-aroylquinoline derivative 温州大学 2023-02-10 CN disclosed
CN-112920113-B Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease 华南理工大学 2022-08-16 CN disclosed
CN-112920113-B Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease 华南理工大学 2022-08-16 CN disclosed
CN-113651752-A Synthesis method of 2-aroylquinoline derivative 温州大学 2021-11-16 CN disclosed
CN-112920113-A Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease 华南理工大学 2021-06-08 CN disclosed
CN-112920113-A Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease 华南理工大学 2021-06-08 CN disclosed