Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.81 |
| ▸ | AR | P10275 | 6/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | RAB9A | P51151 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flumethasone SCHEMBL10532810 | 0.93 | CYP3A4 (0.72) | PGRARCYP3A4HIF1AABCB11 | |
| Flunisolide SCHEMBL221433 | 0.91 | PGR (0.73) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL5381025 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL20169795 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL11911307 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL4555 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL3167856 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL19327158 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL2855052 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 | |
| Flumethasone SCHEMBL11853190 | 0.90 | CYP3A4 (1.00) | PGRARCYP3A4HIF1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253339-B1 | A process for producing stents and corresponding stent | SORIN BIOMEDICA CARDIO SRL (IT) | 2011-12-28 | — | — | EP | disclosed |
| US-8084076-B2 | Process for producing stents and corresponding stents | SORIN BIOMEDICA CARDIO S.R.L. (IT) | 2011-12-27 | — | — | US | disclosed |
| EP-2253339-A1 | A process for producing stents and corresponding stent | Sorin Biomedica Cardio S.r.l. (IT) | 2010-11-24 | — | — | EP | disclosed |
| EP-1449546-B1 | A process for producing stents and corresponding stent | SORIN BIOMEDICA CARDIO SRL (IT) | 2010-10-27 | — | — | EP | disclosed |
| US-20080140186-A1 | PROCESS FOR PRODUCING STENTS AND CORRESPONDING STENTS | SORIN BIOMEDICA CARDIO S.R.L. (IT) | 2008-06-12 | — | — | US | disclosed |
| US-20040167612-A1 | Process for producing stents and corresponding stents | SORIN BIOMEDICA CARDIO S.R.L. (IT) | 2004-08-26 | — | — | US | disclosed |
| EP-1449546-A1 | A process for producing stents and corresponding stent | SORIN BIOMEDICA S.p.A. (IT) | 2004-08-25 | — | — | EP | disclosed |