Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15153946 | 0.82 | TET2 (0.47) | FAAHFFAR1FFAR4 | |
| SCHEMBL3320520 | 0.80 | FAAH (0.65) | FAAHFFAR1GPR84CNR1CNR2 | |
| SCHEMBL17560018 | 0.80 | FAAH (0.65) | FAAHFFAR1GPR84CNR1CNR2 | |
| SCHEMBL17560003 | 0.80 | FAAH (0.65) | FAAHFFAR1GPR84CNR1CNR2 | |
| SCHEMBL15154066 | 0.79 | FFAR4 (0.49) | FFAR1FFAR4GPR84ALDH1A1PPARG | |
| SCHEMBL28562346 | 0.79 | FAAH (0.58) | FAAHFFAR1FFAR4GPR84CNR1 | |
| SCHEMBL17010718 | 0.79 | NAAA (0.52) | FFAR1FFAR4GPR84ALDH1A1PPARG | |
| SCHEMBL29061012 | 0.79 | FAAH (0.58) | FAAHFFAR1FFAR4GPR84CNR1 | |
| SCHEMBL18280797 | 0.79 | NAAA (0.52) | FFAR1FFAR4GPR84ALDH1A1PPARG | |
| SCHEMBL9249024 | 0.79 | GPR84 (0.52) | FAAHFFAR1GPR84CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113082009-A | Compositions and methods for treating aging and age-related diseases and conditions | 加利福尼亚大学董事会 | 2021-07-09 | — | — | CN | disclosed |