SCHEMBL2860050

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861697	0.89	TRPV1 (0.42)	PPARGPPARAEPHX2AURKATPX2
	SCHEMBL2861279	0.86	AKR1C3 (0.50)	AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4
	SCHEMBL2856336	0.85	AKR1C3 (0.45)	PPARGPPARAEPHX2AKR1C3AKR1C2
	SCHEMBL2859767	0.84	LMNA (0.46)	AKR1C3AKR1C2AKR1C1PTGS1
	SCHEMBL2864867	0.83	SLC5A1 (0.42)	AKR1C3AKR1C2PTGS1
	SCHEMBL2865202	0.77	HSD17B1 (0.44)	AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4
	SCHEMBL2858308	0.77	SYNJ2 (0.52)	AKR1C3AKR1C2AKR1C1PTGS1
	SCHEMBL5491546	0.77	SYNJ2 (0.49)	PTGS1
	SCHEMBL2862742	0.76	LMNA (0.48)	HRH3AKR1C3AKR1C2AKR1C1PTGS1
	SCHEMBL15225595	0.76	AKR1C3 (0.47)	AKR1C3AKR1C2AKR1C1PTGS1VNN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.