SCHEMBL2864867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2859767	0.91	LMNA (0.46)	SLC5A1SLC5A2GAAMAPTAKR1C3
	SCHEMBL2856336	0.86	AKR1C3 (0.45)	AKR1C3AKR1C2PTGS1
	SCHEMBL2861765	0.86	NR1H2 (0.41)	SLC5A1SLC5A2NPC1GAAMAPT
	SCHEMBL2861279	0.85	AKR1C3 (0.50)	SLC5A1SLC5A2AKR1C3AKR1C2PTGS1
	SCHEMBL2860050	0.83	PPARG (0.44)	AKR1C3AKR1C2PTGS1
	SCHEMBL2865202	0.83	HSD17B1 (0.44)	GAAAKR1C3AKR1C2PTGS1MEN1
	SCHEMBL2862742	0.82	LMNA (0.48)	GAAMAPTRAB9AAKR1C3AKR1C2
	SCHEMBL5491546	0.80	SYNJ2 (0.49)	GAAMAPTPTGS1MEN1CYP3A4
	SCHEMBL2858308	0.80	SYNJ2 (0.52)	GAAMAPTAKR1C3AKR1C2PTGS1
	SCHEMBL2866366	0.80	TRPA1 (0.36)	AKR1C3AKR1C2PTGS1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.