SCHEMBL28600930

SCHEMBL28600930

[c]1cccc(-c2cncc(-c3ccccc3)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 2/20 0.46
MKNK2 Q9HBH9 2/20 0.46
CYP11B1 P15538 4/20 0.45
CYP11B2 P19099 4/20 0.45
CHRNA7 P36544 2/20 0.44
ATM Q13315 1/20 0.43
CYP19A1 P11511 1/20 0.38
CHRNA3 P32297 3/20 0.37
FDPS P14324 3/20 0.37
CHRNB4 P30926 2/20 0.37
GABRA1 P14867 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
CHRNB2 P17787 2/20 0.37
SMO Q99835 1/20 0.37
NOTUM Q6P988 1/20 0.37
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2449105 0.86 ALDH1A1 (0.43) CYP19A1NOTUM
SCHEMBL11972750 0.84 ALDH1A1 (0.41) ATMNOTUM
SCHEMBL24793 0.84 MAOA (0.43)
SCHEMBL2449354 0.84 MAOA (0.43)
SCHEMBL2960 0.83 ALDH1A1 (0.50) ATMNOTUM
SCHEMBL15063643 0.82 MAOA (0.41)
SCHEMBL28594491 0.82 MKNK1 (0.50) MKNK1MKNK2CYP11B1CYP11B2CHRNA7
SCHEMBL27893679 0.81 CYP2A6 (0.46) CYP11B1CYP11B2CYP19A1GABRA1GABRG2
SCHEMBL21054111 0.81 CYP2A6 (0.46) CYP11B1CYP11B2
SCHEMBL2430850 0.81 CYP11B2 (0.45) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed