Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601191 | 1.00 | USP30 (0.42) | USP30UCHL1MEN1KMT2AALDH1A1 | |
| SCHEMBL28194697 | 0.89 | ALDH1A1 (0.41) | USP30MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL28596876 | 0.89 | ALDH1A1 (0.41) | USP30MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL28600591 | 0.85 | F2RL3 (0.42) | USP30UCHL1ALDH1A1 | |
| SCHEMBL28917974 | 0.85 | F2RL3 (0.42) | USP30UCHL1ALDH1A1 | |
| SCHEMBL28600592 | 0.85 | F2RL3 (0.42) | USP30UCHL1ALDH1A1 | |
| SCHEMBL24208480 | 0.81 | PKM (0.46) | USP30ALDH1A1MAPT | |
| SCHEMBL30740791 | 0.77 | RAB9A (0.48) | ALDH1A1NPSR1LMNAOPRD1ATM | |
| SCHEMBL17002525 | 0.75 | HCRTR1 (0.50) | USP30UCHL1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL30392166 | 0.75 | KDM4E (0.41) | USP30ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107459510-B | Isoxazole compound and application thereof | 华东师范大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-107459510-A | Isoxazole class compound and its application | 华东师范大学 | 2017-12-12 | — | — | CN | disclosed |