Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059345 | 0.81 | GHSR (0.36) | KDM4EACACB | |
| SCHEMBL29090650 | 0.80 | GPR119 (0.47) | KDM4EGPR119 | |
| SCHEMBL28593069 | 0.77 | MEN1 (0.38) | — | |
| SCHEMBL28601340 | 0.76 | HRH3 (0.43) | HRH3CHRNA10CHRNA9HTR7TMEM97 | |
| SCHEMBL19571344 | 0.74 | HRH3 (0.44) | HRH3CHRNA10CHRNA9HTR7TMEM97 | |
| SCHEMBL21020102 | 0.73 | CHRNA10 (0.51) | HRH3CHRNA10CHRNA9HTR7TMEM97 | |
| SCHEMBL6132771 | 0.71 | KDM4E (0.50) | HRH3CHRNA10CHRNA9KDM4ETP53 | |
| SCHEMBL19570981 | 0.71 | HRH3 (0.55) | HRH3CHRNA10CHRNA9HTR7TMEM97 | |
| SCHEMBL31753433 | 0.68 | HRH3 (0.49) | HRH3CHRNA10CHRNA9HTR7TMEM97 | |
| SCHEMBL6134370 | 0.68 | CHRNA10 (0.52) | HRH3CHRNA10CHRNA9KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166059-A | Small molecule MENIN inhibitors | 密歇根大学董事会 | 2021-07-23 | — | — | CN | disclosed |