Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919462 | 1.00 | FPR1 (0.48) | FPR1ABCB1MEN1KMT2ATP53 | |
| SCHEMBL28919461 | 0.92 | MAOA (0.42) | FPR1MEN1KMT2AFPR2RAB9A | |
| SCHEMBL28603922 | 0.91 | MEN1 (0.45) | ABCB1MEN1KMT2ATP53FPR2 | |
| Aza-Flavanone SCHEMBL28606333 | 0.90 | MAOA (0.45) | FPR1FPR2 | |
| SCHEMBL28601605 | 0.89 | KDR (0.39) | FPR1MEN1KMT2AFPR2RAB9A | |
| SCHEMBL28603992 | 0.89 | KDR (0.39) | FPR1MEN1KMT2AFPR2RAB9A | |
| SCHEMBL28599108 | 0.88 | FPR1 (0.47) | FPR1MEN1KMT2AFPR2 | |
| SCHEMBL28608358 | 0.88 | FPR1 (0.47) | FPR1MEN1KMT2AFPR2 | |
| SCHEMBL28608429 | 0.88 | MAPT (0.44) | ABCB1MEN1KMT2ATP53FPR2 | |
| SCHEMBL28614837 | 0.87 | KDR (0.40) | FPR1MEN1KMT2AFPR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | disclosed |